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Nassar, F. (2021). GENOMIC ANALYSIS OF TRANSFORMING GROWTH FACTOR β2 GENE POLYMORPHISM ASSOCIATED WITH PRODUCTIVE PERFORMANCE IN GIZA M-2 CHICKEN LINE. Egyptian Poultry Science Journal, 41(3), 535-547. doi: 10.21608/epsj.2021.195783
Farid Saber Nassar. "GENOMIC ANALYSIS OF TRANSFORMING GROWTH FACTOR β2 GENE POLYMORPHISM ASSOCIATED WITH PRODUCTIVE PERFORMANCE IN GIZA M-2 CHICKEN LINE". Egyptian Poultry Science Journal, 41, 3, 2021, 535-547. doi: 10.21608/epsj.2021.195783
Nassar, F. (2021). 'GENOMIC ANALYSIS OF TRANSFORMING GROWTH FACTOR β2 GENE POLYMORPHISM ASSOCIATED WITH PRODUCTIVE PERFORMANCE IN GIZA M-2 CHICKEN LINE', Egyptian Poultry Science Journal, 41(3), pp. 535-547. doi: 10.21608/epsj.2021.195783
Nassar, F. GENOMIC ANALYSIS OF TRANSFORMING GROWTH FACTOR β2 GENE POLYMORPHISM ASSOCIATED WITH PRODUCTIVE PERFORMANCE IN GIZA M-2 CHICKEN LINE. Egyptian Poultry Science Journal, 2021; 41(3): 535-547. doi: 10.21608/epsj.2021.195783

GENOMIC ANALYSIS OF TRANSFORMING GROWTH FACTOR β2 GENE POLYMORPHISM ASSOCIATED WITH PRODUCTIVE PERFORMANCE IN GIZA M-2 CHICKEN LINE

Article 7, Volume 41, Issue 3, September 2021, Page 535-547  XML PDF (561.45 K)
Document Type: Original Article
DOI: 10.21608/epsj.2021.195783
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Author
Farid Saber Nassar
Animal production, Faculty of Agriculture, Cairo University
Abstract
Transforming growth factor-β (TGF-β) genes considered as one of the large family of multifunctional growth factors that participate in the regulation of a broad range of biological processes in chicken. The current study was conducted to determine genetic polymorphisms of TGF-β2 gene by using PCR-RFLP method in Giza M-2 line which selected for high 6- week live body weight (LBW) for seven generations compared to random bred control (RBC) line. Also, the association between TGF-β2 with productive performance was evaluated for each line. Results indicated that, Giza M-2 line had higher LBW at different ages, LBW at 6 week of age (LBW6), and carcass parts weights and percentages compared to RBC line. In addition, Giza M-2 line had high TGF-β2-BB genotype frequency value (0.80) which explains the positive effects of TGF-β2 gene on LBW and carcass traits in Giza M-2 line compared to RBC line. The current result conducts the broad significant effects of TGF-β2 gene on productive performance of chickens. In addition, the association between these valuable productive traits and TGF β2 gene will effectively develop the selection process by using Marker-Assisted Selection (MAS) in Giza M-2 line breeding program in the near future.
Keywords
chicken; carcass parts; PCR; selection; transforming growth factor
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