• Home
  • Browse
    • Current Issue
    • By Issue
    • By Author
    • By Subject
    • Author Index
    • Keyword Index
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Peer Review Process
  • Guide for Authors
  • Submit Manuscript
  • Contact Us
 
  • Login
  • Register
Home Articles List Article Information
  • Save Records
  • |
  • Printable Version
  • |
  • Recommend
  • |
  • How to cite Export to
    RIS EndNote BibTeX APA MLA Harvard Vancouver
  • |
  • Share Share
    CiteULike Mendeley Facebook Google LinkedIn Twitter
Egyptian Poultry Science Journal
arrow Articles in Press
arrow Current Issue
Journal Archive
Volume Volume 45 (2025)
Volume Volume 44 (2024)
Volume Volume 43 (2023)
Volume Volume 42 (2022)
Volume Volume 41 (2021)
Volume Volume 40 (2020)
Volume Volume 39 (2019)
Volume Volume 38 (2018)
Volume Volume 37 (2017)
Volume Volume 36 (2016)
Issue Issue 4
Issue Issue 3
Issue Issue 2
Issue Issue 1
Volume Volume 35 (2015)
Volume Volume 34 (2014)
EL-Deep, M., Asser, M., Attia, K., Shabaan, M., Eid, Y., Sayed, M. (2016). GLUTATHIONE STIMULATES LIVER ANTI-OXIDANTS RELATED GENES AND REDUCES HEPATIC DYSFUNCTION INDUCED BY DIETARY MYCOTOXINS IN LAYING HENS. Egyptian Poultry Science Journal, 36(2), 389-407. doi: 10.21608/epsj.2016.34561
M. H. EL-Deep; M. H. Asser; kH. M. Attia; M. Shabaan; Y. Z. Eid; M. A. Sayed. "GLUTATHIONE STIMULATES LIVER ANTI-OXIDANTS RELATED GENES AND REDUCES HEPATIC DYSFUNCTION INDUCED BY DIETARY MYCOTOXINS IN LAYING HENS". Egyptian Poultry Science Journal, 36, 2, 2016, 389-407. doi: 10.21608/epsj.2016.34561
EL-Deep, M., Asser, M., Attia, K., Shabaan, M., Eid, Y., Sayed, M. (2016). 'GLUTATHIONE STIMULATES LIVER ANTI-OXIDANTS RELATED GENES AND REDUCES HEPATIC DYSFUNCTION INDUCED BY DIETARY MYCOTOXINS IN LAYING HENS', Egyptian Poultry Science Journal, 36(2), pp. 389-407. doi: 10.21608/epsj.2016.34561
EL-Deep, M., Asser, M., Attia, K., Shabaan, M., Eid, Y., Sayed, M. GLUTATHIONE STIMULATES LIVER ANTI-OXIDANTS RELATED GENES AND REDUCES HEPATIC DYSFUNCTION INDUCED BY DIETARY MYCOTOXINS IN LAYING HENS. Egyptian Poultry Science Journal, 2016; 36(2): 389-407. doi: 10.21608/epsj.2016.34561

GLUTATHIONE STIMULATES LIVER ANTI-OXIDANTS RELATED GENES AND REDUCES HEPATIC DYSFUNCTION INDUCED BY DIETARY MYCOTOXINS IN LAYING HENS

Article 2, Volume 36, Issue 2, June 2016, Page 389-407  XML PDF (714.29 K)
Document Type: Original Article
DOI: 10.21608/epsj.2016.34561
View on SCiNiTO View on SCiNiTO
Authors
M. H. EL-Deep1; M. H. Asser1; kH. M. Attia1; M. Shabaan1; Y. Z. Eid2; M. A. Sayed1
1Animal Prod. Res. Inst, Agric. Res. Center, Ministry of Agric, Egypt, Egypt
22 Poultry Production Dept, Fac. of Agriculture, Kafrelsheikh University, Egypt.
Abstract
This study was performed to evaluate the protective effects of feeding reduced glutathione (GSH) against hepatic dysfunctions related to dietary aflatoxicosis in Inshas chickens (a local Egyptian chicken strain). 5 ppm of GSH were used with 500 ppm of aflatoxin B1 (AFB1) /kg diet administrated. In total, 96 chickens were divided into 4 treatments with 3 replicates. T1 was the negative control. T2was the positive control group (AFB1). Groups T3 and T4 were administrated with GSH, and GSH+ AFB1, respectively. At the end of the experiment (28-38) wk of age, samples were collected for analysis. The results showed that AFB1 has significant potency for increasing aspartate transaminase (AST), creatinine in blood, thiobarbituric acid reactive substances (TBARS) in muscle , while reducing the plasma α-tocopherol content, antioxidants enzymes (glutathione peroxidase (GSH-Px), catalase (CAT), superoxide dismutase (SOD) and total antioxidant capacity) in blood of chicken. In addition, the negative effects of AFB1 on mRNA for antioxidant enzymes (GPX, SOD and CAT), hepatosomatic index (HSI), lipid peroxidation on birds aflatoxicosis were recorded in this study, also the efficacy of GSH for ameliorating aflatoxicosis were recorded. Moreover, these results showed that the ability of GSH when use with aflatoxicosis to counteract the toxic effects of AFB1 on chickens. Additionally, the GSH-Px (T3) were enhanced the antioxidative status. Finally, the optimal levels of GSH and method of used for detoxification of aflatoxin effects need more studies.
Keywords
Aflatoxin B1- Glutathione- Antioxidants and Chickens
Statistics
Article View: 266
PDF Download: 447
Home | Glossary | News | Aims and Scope | Sitemap
Top Top

Journal Management System. Designed by NotionWave.