Abd El-Azeem, N., Abdel Magied, H. (2025). Effect of hydrolysable tannin and grape seed extract supplementation on growth performance, antioxidative status and immune response of growing rabbits. Egyptian Poultry Science Journal, (), -. doi: 10.21608/epsj.2025.56475.1135
Noha Mahmoud Abd El-Azeem; hemat abdel aal Abdel Magied. "Effect of hydrolysable tannin and grape seed extract supplementation on growth performance, antioxidative status and immune response of growing rabbits". Egyptian Poultry Science Journal, , , 2025, -. doi: 10.21608/epsj.2025.56475.1135
Abd El-Azeem, N., Abdel Magied, H. (2025). 'Effect of hydrolysable tannin and grape seed extract supplementation on growth performance, antioxidative status and immune response of growing rabbits', Egyptian Poultry Science Journal, (), pp. -. doi: 10.21608/epsj.2025.56475.1135
Abd El-Azeem, N., Abdel Magied, H. Effect of hydrolysable tannin and grape seed extract supplementation on growth performance, antioxidative status and immune response of growing rabbits. Egyptian Poultry Science Journal, 2025; (): -. doi: 10.21608/epsj.2025.56475.1135
Effect of hydrolysable tannin and grape seed extract supplementation on growth performance, antioxidative status and immune response of growing rabbits
Articles in Press, Accepted Manuscript, Available Online from 19 May 2025
1Animal Production Research Institute, Rabbit and turkey department
2animal production research institute - agricultural research center
Abstract
sixty weaned male New Zealand White rabbits 6 weeks of age with an average initial body weight 684±20g were divided randomly into four treatments, fifteen animals/each. First group fed the basal diet without any additive as a control group, while 2nd ,3rd and 4th fed basal diet with hydrolysable tannin as Silvafeed® ATX (HT, 1.5 g/kg diet), grape seed extract (GSE, 0.5 g/kg diet) and mix between both HT and GSE, respectively. The results showed that, compared with other groups, the mix group between HT and GSE had the best body weight gain and feed conversion ratio. whereas, there were no significant effect of feed additives on carcass characteristics. The results also showed an increase in the antioxidant enzymes (Catalase) in blood and rabbit’s meat by adding mix between both HT and GSE of rabbit’s diet. However, Malondialdehyde (MDA) was reduced (p ≤ 0.001) with all treated groups compared to control in both plasma and meat. Total protein, globulin and Immunoglobulin (G and M) were significantly increased in the group of rabbits fed the mix additives. In contrast, plasma total cholesterol and triglycerides reduced numerically in all treated groups. The results showed no adverse effect on both liver and kidney function with the addition of HT and GSE. The economical efficiency ratio also increased with the treatment groups, especially the mixture between HT and GSE. The results of the study revealed that HT and GSE were useful as a natural protection against oxidative stress factors resulting from rearing rabbits in the summer months by maintain performance, antioxidant status and immunity in a good shape.
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